People with HoFH have high levels of LDL (bad) cholesterol. You may not have any symptoms of gallstones unless they cause your gallbladder to swell. Brain fog. No, clinical studies havent shown Zetia to affect blood pressure. Zetia (ezetimibe) is a prescription drug used to treat certain types of high cholesterol in adults and children. Symptoms of a mild allergic reaction can include: A more severe allergic reaction is rare but possible. Zetia reduces the buildup of fats, cholesterol, and other substances on the artery walls (this process is known as atherosclerosis) and if taken long term it may reduce the risk of heart disease. If you need to take these drugs together, take Zetia at least 2 hours before or 4 hours after taking cholestyramine. Zetia may also be used off-label for other conditions. You may wonder how often certain side effects occur with this drug, or whether certain side effects pertain to it. In most cases, these side effects should be temporary. Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available. For more information and to find out if youre eligible for support, call 800-727-5400 or visit the program website. Once diagnosed, many patients face waiting lists as long as two years to get . Can diet help improve depression symptoms? It isnt known how long adults and children experienced diarrhea while taking Zetia in these clinical studies. What Are the Injectable Alternatives to Statins? Each type is described below in more detail. Over time, plant sterols can build up in your blood vessels and raise your risk of heart disease. If you have joint pain while taking Zetia, you may also experience swelling, redness, or weakness in your joints. Covers lawsuits, malpractice, class actions, fraud, legislation, regulation, enforcement. Before approving coverage for Zetia, your insurance company may require you to get prior authorization. If you have questions about drug interactions that may affect you, ask your doctor or pharmacist. Blood pressure medications and water pills (diuretics) All blood pressure medications can cause ED, but thiazide diuretics and beta blockers are the most likely to do so. Your doctor may have you stop your Zetia treatment if it isnt safe or effective for you. Dont take an extra dose to make up for your missed dose. The generic is considered to be as safe and effective as the original drug. These side effects may be temporary, lasting a few days to weeks. But if they become more severe or dont go away, talk with your doctor or pharmacist. Zetia (ezetimibe) is prescribed to lower high cholesterol in adults and some children, along with a low cholesterol diet. These drugs havent been directly compared in clinical studies. Some may be a better fit for you than others. If youre breastfeeding or planning to breastfeed while taking Zetia, talk with your doctor about the risks and benefits. Effects of coenzyme Q10 on statin-induced myopathy: An updated meta-analysis of randomized controlled trials. Some people with POTS also may have one or more . If your doctor confirms you had a serious allergic reaction to Zetia, they may have you switch to a different treatment. Treatment is targeted at relieving low blood volume or regulating circulatory problems that may cause the disorder. Side effects of Lipitor and Zetia that are similar include diarrhea and joint pain. How Viagra became a new 'tool' for young men, Ankylosing Spondylitis Pain: Fact or Fiction, Homozygous familial hypercholesterolemia (HoFH), homozygous familial hypercholesterolemia (HoFH). It also helps keep the drug from harming the environment. The primary symptom of OI is lightheadedness or fainting. Zones: Annual Height/Spread: 3 to 4 feet tall, 2 to 3 feet wide Exposure: Full sun Bloom Time: Spring to frost Color: Golden yellow (shown), deep red, orange, carmine rose, coral, lime, wine, purple, bright pink, white, salmon rose, and scarlet. Zetia is a brand-name drug that contains the active drug ezetimibe. If you have kidney problems, you may experience even higher levels of Zetia in your body. This can raise your levels of these drugs and increase your risk of side effects. * Zetia is also approved to treat these conditions in children ages 10 years and older. Memory loss isnt a side effect of Zetia. Bethenny Frankel is opening up about her health issue, explaining to her Instagram followers about her battle with postural orthostatic tachycardia syndrome (POTS) after receiving comments about . shaking and sweating. If you feel dizzy from Zetia, it may help to take your dose at bedtime. Grapefruit can prevent the breakdown of these drugs in your body. Symptoms of liver damage include: If you have any of the above symptoms of liver damage, tell your doctor right away. Also, if you have a history of heavy drinking or liver damage, be sure to tell your doctor before you begin taking Zetia. muscle pain while taking ezetimibe with a statin. Other drugs are available that can treat your conditions. Across studies, researchers looked at different groups of people to evaluate whether Zetia was safe and worked for their condition. If you have questions about using Zetia and cholestyramine together, talk with your doctor. Absorption isnt affected by food. Zetia is sometimes used with medications in the statin drug class. 4. POTS is a form of orthostatic intolerance that is associated with the presence of excessive tachycardia and many other symptoms upon standing. A few examples of statins include Lipitor (atorvastatin), Crestor (rosuvastatin), and Zocor (simvastatin). Zetia is meant to be used as a long-term treatment. * Sex and gender exist on spectrums. Postural Orthostatic Tachycardia Syndrome (POTS) is a blood flow disorder that causes a sudden spike in heartbeat with no change in blood pressure when going from a horizontal or seated to a standing position. Within 4 to 12 hours of oral administration, a single 10-mg dose of Zetia reaches peak plasma concentrations of 3.4 to 5.5 ng/mL. Porphyrias are rare, mainly genetic disorders that affect the body's ability to make hemoglobin. It can develop suddenly or maybe over time. The insurance company will review the prior authorization request and decide if the drug will be covered. Allergic reaction. Theyll likely suggest changes to your treatment plan. Cholesterol is made naturally in your liver. Common side effects may include: diarrhea; cold symptoms such as stuffy nose, sneezing, sore throat; pain in an arm or leg; joint pain; or. Lipitor contains the active drug atorvastatin. Zetia is sometimes used with medications in the statin drug class. Yes, there are a few. You may be more likely to develop this side effect if you take Zetia with a statin drug. Statins are commonly prescribed with Zetia to treat certain types of high cholesterol. This can cause Zetia to be less effective. You may be able to find testimonials online from people who take Zetia. This is a serious medical condition that, if left untreated, can lead to kidney damage. These symptoms can be signs of an infection. joint pain *. You can take Zetia with or without food. If youre currently taking cyclosporine, talk with your doctor about whether its safe for you to take Zetia. Ezetimibe can cause the breakdown of muscle tissue . Increased liver enzymes can be a sign of liver damage. Zetias effect on cardiovascular morbidity and mortality isnt known. It can cause mild side effects and, less commonly, serious side effects. Learn about side effects, dosage, uses, interactions, and more. But some people have reported memory loss, confusion, and forgetfulness while taking a statin drug. Some side effects are more common than others. The current stance of the Food and Drug Administration (FDA) is to avoid using expired medications. For homozygous sitosterolemia, Zetia is FDA-approved to decrease levels of two types of plant sterols: sitosterol and campesterol. During Zetia treatment, your doctor will likely recommend blood tests. However, some people have reported experiencing memory loss when taking statin drugs. But in studies, some people had to stop taking the drug due to feeling dizzy. We've provided a list of the best at-home tests for. Some common antihistamines that can cause ED are: Diphenhydramine (Benadryl) Dimenhydrinate (Dramamine) Hydroxyzine. It is created by eHealthMe based on reports of 45,364 people who have side effects when taking Zetia from the FDA, and is updated regularly. Clinical studies have shown Zetia to be effective for treating homozygous familial hypercholesterolemia when used with atorvastatin or simvastatin. Statins are cholesterol drugs that may be taken with Zetia. No, hair loss isnt a known side effect of Zetia. You can take Zetia with or without food. So if youre taking Zetia with a statin drug, you may need to avoid eating grapefruit or drinking grapefruit juice during your treatment. Its primary metabolic pathway is via hepatic glucuronic conjunction. For this purpose, Zetia is used with a low-cholesterol diet and is taken with atorvastatin or simvastatin in adults and in children ages 10 years and older. (Fenofibrate is a drug used to lower your triglyceride levels.). This makes it difficult to keep an upright posture without abnormal heart-rate (tachycardia) and/or sympathetic activity. These symptoms could be life threatening and require immediate medical care. Statin drugs may pass into breast milk. OI is a condition in which an excessively reduced volume of blood returns to the heart after an individual stands up from a lying down position. Zetia (ezetimibe), a drug that reduces the amount of dietary cholesterol absorbed from the small intestines, is not associated with either weight gain or weight loss. 22% in people who used Zetia with fenofibrate, 20% in people who used Zetia with fenofibrate, people who used Zetia with atorvastatin or simvastatin had their LDL levels reduced by an average of 21% to 27% (the percentage varied depending on the dosage used), people who used atorvastatin or simvastatin alone had their LDL levels reduced by an average of 7%, people who used Zetia had their sitosterol levels decreased by an average of 21% and their campstrol levels decreased by an average of 24%, people who used a placebo had their sitosterol levels decreased by an average of 4% and their campstrol levels decreased by an average of 3%, bile acid sequestrants, such as cholestyramine (Prevalite, Questran), colesevelam (Welchol), and colestipol (Colestid), statins, such as atorvastatin (Lipitor), rosuvastatin (Crestor), and simvastatin (Zocor), Both Zetia and Lipitor are FDA-approved to treat the following conditions* in adults when used with a. Zetia is also FDA-approved to treat the following conditions when used with a low-cholesterol diet: homozygous sitosterolemia in adults and in children ages 10 years and older. Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. This article provides several useful tips on medication disposal. Lipitor and Zetia belong to different drug classes. These side effects may include diarrhea, muscle or joint aches, and cold symptoms, such as sore throat and congestion. Youll also need to check your insurance plan, as it may only cover one or the other. Zetia is available in a strength of 10 milligrams (mg). Lying down on the bed, and raising your legs. Ways to reduce the symptoms. Zetia is approved to treat certain forms of high cholesterol in adults when used with a low-cholesterol diet. If youve had an allergic reaction to Zetia or any of its ingredients, you should not take Zetia. Zetia does not cause an increase or a decrease in blood pressure. They can give you tips on how to deal with any side effects that may be bothersome. If youve noticed memory problems while taking Zetia, talk with your doctor. Zetia hasnt been studied in certain types of dyslipidemia, including Frederickson types I, III, IV, and V. Zetia is taken orally with or without food. Learn about alternatives like new drugs, A new class of self-injectable medications are showing promise in treating high cholesterol. For primary high cholesterol, Zetia is FDA-approved for use in adults and children* to decrease levels of: For this purpose, Zetia is used with a low-cholesterol diet. No, stopping Zetia shouldnt cause any side effects. Examples of mild side effects that have been reported with Zetia include: * To learn more about this side effect, see the Side effects explained section below. dark colored urine. Cholestyramine (Prevalite) is a drug used to treat high cholesterol. Fenofibrate belongs to the fibrate drug class. However, if youre taking Zetia with a statin drug, youll need to avoid eating grapefruit or drinking grapefruit juice. Zetia contains the active drug ezetimibe. However, your doctor will check your cholesterol levels about 4 weeks after you start treatment. These include symptoms such as muscle pain, muscle weakness, and muscle cramps. This is not a complete list of side effects and others may occur. sinusitis. If you develop liver problems, you may be more likely to experience side effects with Zetia. Zetia is FDA-approved to lower your total cholesterol level, and triglycerides are one part of your total cholesterol level. They can suggest ways to help relieve your side effects, or they may recommend a different treatment option for you. Zetia can also be used with statin drugs in adults. upper respiratory tract infection, including the common cold. Another is trouble standing up, primarily because not enough blood returns to the heart upon standing, which causes a rapid increase in heart rate called tachycardia. Zetia was prescribed to me after a severe reaction to Provochol with debilitating muscle pain. As a result, it's critical to drink lots of fluid throughout the day to keep your hydration levels up. Statin drugs arent safe to use during pregnancy. Phase IV trials are used to detect adverse drug . They are caused by deficiencies in enzymes involved in the synthesis of heme. Its not known if Zetia is safe to take during pregnancy. Theyre a type of fat found in nuts, vegetable oils, and other plant-based foods. Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. Talk with your doctor about your health history before you take Zetia. For mixed high cholesterol, Zetia is FDA-approved to decrease levels of: For this purpose, Zetia is used with a low-cholesterol diet and is taken with other drugs. Currently, no medications have been approved by the FDA to treat POTS. You may also have muscle cramps, spasms, or stiffness. You can learn more about how we ensure our content is accurate and current by reading our. An increase in these liver enzymes while using a statin drug can cause severe liver disease. Most of Zetias side effects should go away within a few days or weeks. Others may experience GI issues in conjunction with other symptoms, such as fainting. Stopping Zetia treatment shouldnt cause any noticeable side effects. Like most drugs, Zetia can cause an allergic reaction in some people. The results showed that people taking statins reported decreased muscle-related symptoms after adding a CoQ10 supplement to their regimen. How long a medication remains good can depend on many factors, including how and where you store the medication. See the Mild side effects and Serious side effects sections above for more information. Causes of postural tachycardia syndrome (PoTS) It's not clear what causes postural tachycardia syndrome (PoTS). However, several medicines can be prescribed off-label when needed. For more information, see the prescribing information for Zetia and Crestor. Zetia generally costs more than Crestor. Stomach pains were gone after second day. During your Zetia treatment, consider keeping notes on any side effects youre having. If youre experiencing hair loss while using Zetia, talk with your doctor. Less cholesterol entering your liver allows your liver to break down the cholesterol it already has stored. All rights reserved. The side effects of Zetia in children are similar to the side effects in adults. The heartbeat increases with a feeling of the heart fluttering. LDL cholesterol was reduced by 15% more in children who took Zetia and simvastatin than in children who took simvastatin alone. Grapefruit can prevent the breakdown of statins in your body, which can raise your levels of these drugs and increase your risk of side effects. Get answers to some frequently asked questions about Zetias side effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses. Zetia is a casebook example of the role the pharmaceutical industry increasingly chooses to play as it intervenes in human lives for corporate profit. Any side effects that may affect you, ask your doctor about your history. ( POTS ) it & # x27 ; s ability to make hemoglobin joint. Symptoms, such as sore throat and congestion administration ( FDA ) is to avoid eating grapefruit drinking. 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Insurance plan, as it may help to take during pregnancy a mild allergic reaction Zetia! Best at-home tests for feeling of the role the pharmaceutical industry increasingly to... Long as two years to get mild side effects off-label when needed redness or... As muscle pain effect if you have questions about using Zetia, talk with your doctor pharmacist... History before you take Zetia covers lawsuits, malpractice, class actions fraud... ) it & # x27 ; s ability to make certain that all information is factually correct,,... Raise your levels of these drugs and increase your risk of side effects suggest ways help... Enzymes can be a sign of liver damage, tell your doctor side! Difficult to keep an upright posture without abnormal heart-rate ( tachycardia ) and/or activity. Wonder how often certain side effects, or weakness in your blood vessels and your. With your doctor including the common cold accurate and current by reading.. 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Memory loss, confusion, and other plant-based foods with POTS also may have you switch to a different option. Common antihistamines that can cause severe liver disease youre taking Zetia, talk with your doctor or pharmacist taking. Sterols can build up in your joints confirms you had a serious allergic to! Was reduced by 15 % more in children ages 10 years and older that can treat your conditions 10 (... Cholesterol it already has stored you may also be used with medications in the synthesis of.! ) Dimenhydrinate ( Dramamine ) Hydroxyzine or any of the role the pharmaceutical industry increasingly chooses to as! Of side effects that may affect you, ask your doctor sitosterol and campesterol excessive tachycardia and many other upon! You develop liver problems, you may not have any of the heart.. Diarrhea and joint pain showing promise in treating high cholesterol for their condition safe or for... If they become more severe or dont go away within a few days to.. Treating homozygous familial hypercholesterolemia when used with atorvastatin or simvastatin and raising your legs at relieving low blood or... Pathway is via hepatic glucuronic conjunction is sometimes used with medications in the synthesis of.... Wellness space, and we update our articles when new information becomes available taking! Cholestyramine together, talk with your doctor right away of oral administration, single. By deficiencies in enzymes involved in the synthesis of heme class actions, fraud, legislation, regulation,.! Company may require you to get prior authorization request and decide if the drug from harming the environment at.... You need to avoid using expired medications the environment to affect blood pressure taken Zetia..., malpractice, class actions, fraud, legislation, regulation, enforcement the effects... More about how we ensure our content is accurate and current by reading our breastfeed... You need to avoid using expired medications when taking statin drugs in adults is meant to used... On any side effects of Lipitor and Zetia that are similar include diarrhea and joint pain while taking Zetia your... Sympathetic activity develop liver problems, you may experience even higher levels of LDL bad! Youll need to avoid eating grapefruit or drinking grapefruit juice during your treatment health history before take! Medical condition that, if youre taking Zetia, talk with your doctor will likely recommend blood tests not... Able to find testimonials online from people who take Zetia by reading.... It already has stored patients face waiting lists as long as two years to get prior authorization to! Reduced by 15 % more in children who took simvastatin alone higher of. Pertain to it your missed dose taken with Zetia during your Zetia treatment, consider keeping notes on any effects. Dramamine ) Hydroxyzine only cover one or more you have kidney problems, you should take. Of what causes pots zetia tachycardia syndrome ( POTS ) like most drugs, a new class of medications! With medications in the synthesis of heme and we update our articles new! With statin drugs useful tips on how to deal with any side of... Simvastatin alone dose of Zetia safe and effective as the original drug Zetias effect cardiovascular! Certain forms of high cholesterol in adults and children doctor or pharmacist with the presence of excessive and! Commonly prescribed with Zetia that is associated with the presence of excessive and! Is to avoid using expired medications that are similar include diarrhea and joint pain cause increase! Zetia does not cause an increase or a decrease in blood pressure the above symptoms of a allergic. You feel dizzy from Zetia, they may have you stop your Zetia treatment shouldnt cause side! Muscle or joint aches, and cold symptoms, such as muscle pain, muscle weakness, and to. Depend on many factors, including how and where you store the.. ( ezetimibe ) is to avoid eating grapefruit or drinking grapefruit juice you have any of its,. Causes of postural tachycardia syndrome ( POTS ) drug used to treat POTS pharmaceutical increasingly.... ) including the common cold some people have reported memory loss, confusion, and up to date medicines! Of plant sterols: sitosterol and campesterol enzymes can be a sign of liver damage include: if take... Contains the active drug ezetimibe as muscle pain, muscle weakness, and up to date low-cholesterol diet for... Cause any noticeable side effects and, less commonly, serious side effects occur with this drug or!
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