Glad you got your hearing back! Zyrtec (cetirizine hydrochloride) is an antihistamine that treats symptoms, such as itching, runny nose, watery eyes, and sneezing from hay fever ( allergic rhinitis) and other allergies, such as allergies to molds and dust mites. It was torture that lasted over a month. How long does it stay in the body? Often the cause of heart palpitations can't be found. I wish you the best of luck through your withdrawal. I was on Costco generic Zyrtec for so many years, Ive lost count! Im in week 2 of the anxiety and it is terrible. Week 2 Upon starting my second week of withdrawal, the itching was still pretty constant, but the intensity had lowered. My mom is going through the same thing. As my body finds homeostasis again in its histamine levels, I can confidently say I am free from Zyrtec and no longer dependent on a pill that forced my body to become addicted to it. I dont understand either why there are no warnings on these drugs. It helped. Ive already ordered all of the helpful items you recommended such as the body scrubber and the lotion to help alleviate the symptoms. -Maximum dose: 5 mg/day You can do this! I stumbled across an open access (ie free) medical article from 2019 that may be helpful for doctors and allergists. We have received a huge number of reports about post-cetirizine itch. Read up on the difference between first generation H1-antihistamines (diphenhydramine (Benadryl) and hydroxyzine (Vistaril/Atarax) and second generation H1-antihistamines (fexofenadine (Allegra), loratidine (Claritin), cetirizine (Zyrtec)). I really didnt want to use either so I just left them in the cupboard. It is considered a second-generation non-sedating antihistamine. And for about a week, the hives didnt return. I was scratching so hard it led to welts and swelling. I left it on my scalp and body until I felt the tingle, then rinsed off. However, Dr. Lin says antihistamines alone are "not bad for the heart in otherwise healthy people.". Do not allow liquid medicine to freeze. Common gastrointestinal (GI) side . During these early days, I tried to keep busy. And my doctor just looked at me blankly as I reported this outcome. In the drug realm, antihistamines such as diphenhydramine (Benadryl), chlorpheniramine (Chlor-Trimeton), cetirizine (Zyrtec), and loratadine (Claritin) can help with a stuffy nose are safe for the heart. We contacted the FDA about this discontinuation syndrome. Initially, there seemed to be skepticism, but eventually the agency published research confirming this reaction (Therapeutic Advances in Drug Safety, July 5, 2019). Went to an allergist that did a blood allergen test. ANYONE gone through this a second time? Now I want to plan and get off this ridiculous medicine. My hands, arms, and legs were occupied, and it was a welcome relief to both my brain and my skin to ignore the itch and give my skin a break. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. I started taking the Zyrtec about 8 years ago when I became itchy and a friend with dermatographia recommended it. As Susan said, this feels similar to scabies mites, which I have had years ago. Best of luck to you! [Ref], Very common (10% or more): Somnolence (up to 14.3%), headache (up to 14%), Frequency not reported: Altered sense of taste, paresthesia, hypertonia, tremor, abnormal coordination/incoordination, ataxia, hyperesthesia, hyperkinesia, hypoesthesia, migraine, paralysis, twitching, parosmia, taste loss/perversion, Postmarketing reports: Convulsions, dysgeusia, dyskinesia, dystonia, syncope, amnesia, vertigo, memory impairment[Ref], Common (1% to 10%): Dry mouth, nausea, diarrhea, vomiting, abdominal pain, Frequency not reported: Tongue disorder, constipation, flatulence, increased salivation, aggravated tooth caries, eructation, gastritis, hemorrhoids, melena, rectal hemorrhage, stomatitis/ulcerative stomatitis, tongue discoloration/edema, enlarged abdomen[Ref], Common (1% to 10%): Pharyngitis, rhinitis, coughing, epistaxis, Frequency not reported: Dyspnea, respiratory disorder, bronchospasm, upper respiratory tract infection, dysphonia, bronchitis, hyperventilation, increased sputum, pneumonia, sinusitis, nasal polyp[Ref], Frequency not reported: Earache, tinnitus, fever, pain, rigor, thirst, deafness, ototoxicity, accidental injury, face edema, leg edema, malaise, Postmarketing reports: Asthenia, stillbirth[Ref], Frequency not reported: Nervousness, impaired concentration, confusion, decreased libido, abnormal thinking, anxiety, depersonalization, emotional lability, euphoria, paroniria, sleep disorder, Postmarketing reports: Agitation, aggression/aggressive reaction, depression, hallucination, tic, suicidal ideation/suicide[Ref], Frequency not reported: Back pain, myalgia, arthralgia, bone disorder/fracture, leg cramps, arthritis, arthrosis, muscle weakness[Ref], Frequency not reported: Pruritus/intense itching, increased sweating, acne, alopecia, bullous eruption, dermatitis, dry skin, eczema, erythematous rash, furunculosis, hyperkeratosis, hypertrichosis, maculopapular rash, photosensitivity/photosensitivity toxic reaction, purpura, seborrhea, skin disorder/nodule, Postmarketing reports: Rash, urticaria, angioneurotic edema, fixed drug eruption, acute generalized exanthematous pustulosis (AGEP)[Ref], Frequency not reported: Eye abnormality, periorbital edema, abnormal vision, eye pain, conjunctivitis, ptosis, visual field defects, blindness, glaucoma, ocular hemorrhage, xerophthalmia, periorbital edema/eye swelling, Postmarketing reports: Accommodation disorder/loss of accommodation, blurred vision, oculogyration, orofacial dyskinesia[Ref], Frequency not reported: Polyuria, urinary retention, urinary tract infection, dysmenorrhea, hematuria, micturition frequency, urinary incontinence, female breast pain, intermenstrual bleeding, leukorrhea, menorrhagia, vaginitis, Postmarketing reports: Dysuria, enuresis[Ref], Frequency not reported: Flushing, palpitations, tachycardia, edema/general edema, chest pain, cardiac failure, hypertension, hot flashes, peripheral edema, pallor, Postmarketing reports: Severe hypotension[Ref], Frequency not reported: Increased appetite, anorexia, increased weight, dehydration, diabetes mellitus[Ref], Frequency not reported: Reversible transaminase elevations, Postmarketing reports: Abnormal hepatic function (increased transaminases, alkaline phosphatase, GGT, bilirubin), cholestasis, hepatitis[Ref], Frequency not reported: Allergic reactions/delayed allergic reactions, Postmarketing reports: Hypersensitivity, anaphylactic shock[Ref], Postmarketing reports: Thrombocytopenia, hemolytic anemia[Ref], Postmarketing reports: Glomerulonephritis[Ref]. -Maximum dose: 10 mg/day, 6 months to 2 years: Every day since then the itch has subsided more and more. I was getting worried maybe it was something more serious. De Sutter A, Saraswat A, van Driel M. Antihistamines for the common cold. Albeit, smaller ones that the initial attack in 2018. Dr. Woodcock has asked me to respond. I still itch a little every night (I wonder if I have a histamine intolerance) and I do fine with an Allegra or Benadryl. Cerner Multum, Inc. "Australian Product Information." Best of luck to you! I mentioned the theory that it was a response to stopping Zyrtec and she read through all of the medical literature at her disposal, said there was nothing out there suggesting that was a thing and then hastened to add that the first rule of medicine is to never discount an idea or a too-coincidental situation. The itching and rash are very bad. Im hoping that it wont last long, and I will be able to see if the Zyrtec has contributed to the unexplained weight gain! Hypertension occurs in less than two percent of patients taking Zyrtec and the mechanism of the blood pressure elevation in those patients is unknown 2. . This needs to get researched! Thank you for writing this article, it makes me feel like Im not alone in this and there are a lot of people going through the same problem. We suspect that we (The Peoples Pharmacy) represents the discussed on the internet part of that background. Older adults may need to take a lower than normal dose. Now, Im on once a week. Ive been taking Zyrtec for years and it got to the point that its not even helping anymore so I decided to quit it. I was able to get an urgent appointment with the allergy doc and he immediately recognized my symptoms as Zyrtec withdrawal. All rights reserved. Currently you have JavaScript disabled. It was titled: Intense pruritus or itching emerging after discontinuation of cetirizine has been the subject of postmarketing reports submitted to the U.S. Food and Drug Administration (FDA), published in the medical literature, and discussed on the internet. get a good brand. She also holds a Doctorate of Medicine from the University of New Mexico. At first, Id break out in response to heat or severe stress. Yes, I did itch every now and then, but staying away from alcohol and being well-hydrated was the combination that worked for me. I am experiencing anxiety real bad right now. As a result, we suspect that most people are unaware of this potential problem. The next time, I cut one in half for 3 days. When I reached the 3rd week the itchiness started disappearing but I started getting allergy symptoms like coughing and chest tightness( difficulty breathing). My scalp, my ears (even inside), my mouth and throat, my eyes were itching like hell. Im being patient so my severe itching and hives also go away. Zyrtec is available in generic form and over-the-counter ( OTC ). I had terrible itching for about a week, but it went away. -Maintenance dose: 2.5 mg orally once to 2 times a day Ive been on Xyzal and Benadryl for years. Well done you! -Maintenance dose: 2.5 mg orally once to 2 times a day Recreational marijuana is legal in Illinois and I have a medical marijuana license due to my degenerative disc disease. Please keep in mind I was micro-dosing THC, only ingesting 5 mg of THC at a time. In the shower I bring the water to almost scalding and then all the way down to cold and the few hours after are the longest periods of relief. So its a circle of constantly having to take it, and yet, I didnt have the slightest idea getting off Zyrtec was the direct cause. We comply with the HONcode standard for trustworthy health information. Best of luck . I called the clinical nurse at my Doctors office. Red wine is high in histamines, compared to white wines and sparkling wines (which still flared up my itching a bit). Glad you found some helpful tips in this post. Its important for you to be your number one advocate at this time and take care of yourself first. Your reactions could be impaired. I dont necessarily take it for allergies, but for silent reflux. I earn a small commission if you make a purchase.). A few years ago we contacted one of the highest officials at the FDA. Ive had the best luck with Benadryl (with breakthrough itching) as it doesnt seem to have any withdrawal symptoms. The 5th day the tingling of my tongue and lips was gone. Apparently it takes as many as 6 weeks after being cured for your body to work through the remaining allergens left by the mites under your skin. I have no hives, just incredible itchiness and I dont want to take medicine for it. You can get through this! 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